Yes. In studies with healthy volunteers, LSD usually causes a mild to moderate, temporary rise in blood pressure and heart rate, most noticeable in the first hours.
Effects scale with dose. Very low doses around 10 to 20 micrograms show little to no meaningful change for most participants, while full doses around 100 to 200 micrograms produce clearer increases that tend to peak near 1 hour and drift back toward baseline over about 10 to 12 hours.
These changes are often described as modest in healthy people, but higher doses and conditions like uncontrolled hypertension or cardiovascular disease may add risk. I cannot verify your individual situation.
For a concise overview, see this Q&A on LSD and blood pressure: link. Hope this helps.