Short answer: yes, actigraphy-based measures of sleep and rest-activity were able to flag higher risk of depression relapse in a one-year observational cohort.
In a Canadian study of 93 adults with a history of major depression who were relatively stable at baseline, continuous actigraphy was summarized every two weeks and relapse was stringently defined. The report in JAMA Psychiatry describes about 32,000 complete actigraphy days over a median 46-week follow-up.
Lower sleep regularity, lower relative amplitude of rest-activity, lower sleep efficiency, and more wake after sleep onset or nighttime activity were each linked to roughly doubled relapse risk. Notably, lower relative amplitude remained predictive even after accounting for concurrent depressive symptoms. This study shows association, not causation, so it cannot prove that sleep disturbance causes relapse.
Bottom line: actigraphy shows promise as a scalable marker to monitor relapse risk, but broader validation and prospective testing are needed before routine clinical adoption. Hope this helps.