What is a good interval between psychedelic sessions?

There is no single schedule that suits everyone. A thoughtful interval usually considers short-term tolerance, recovery of neurochemistry, and time to integrate personal insights and emotions.

Classic psychedelics (psilocybin and LSD)

Tolerance tends to fade within about a week, yet many people prefer 2 to 4 weeks between full sessions to allow integration and stability. After deeper or more demanding experiences, waiting one to several months is commonly chosen.

MDMA

Because MDMA strongly affects serotonin release and reuptake, longer gaps are often discussed. A minimal spacing of roughly 3 to 5 weeks is frequently mentioned, and many opt for 6 to 8 weeks or more.

Ceremonial or retreat settings

Some traditions, such as ayahuasca retreats, include multiple sessions on consecutive days within a structured program, followed by a longer integration period that can extend for months.

Practical guideline

A four-week interval is often seen as a workable balance between continuity and time for integration. Shorter spacing may be used for low doses or logistics, but is generally viewed as less ideal. After intense or emotionally heavy sessions, longer intervals are commonly preferred.

What can and cannot be verified

Exact timelines vary by person and substance, and there is no definitive research-based rule that fits everyone. Consider your current mental state, physical well-being, and support for integration when deciding on timing. For community perspectives, see the Q&A on spacing sessions at Tripforum.

Conclusion

Physiological recovery can be relatively quick, but the most useful interval is usually guided by integration and stability. For most situations, leaving several weeks to a few months between significant sessions is a prudent approach.