There is no clear winner for OCD. Evidence is limited, and I cannot verify that psilocybin or LSD is superior overall.
In practice, many therapists start with psilocybin because it has a larger research footprint in OCD and a shorter duration, which can make sessions easier to structure.
LSD lasts longer and some people report stronger cognitive and visual engagement. Anecdotally, this can feel helpful for deeply rooted patterns or highly analytical thinkers, but this is not established by controlled studies.
Some practitioners also mention the “wizard flip,” a combined LSD and psilocybin session, though scientific data are lacking; it is discussed here: wizard flip. The better choice depends on individual response, goals, and professional guidance.
Hope this helps you weigh the options.