Some people choose LSD therapy over psilocybin not because it is more effective, but because of how the experience feels. The clinical literature is currently larger for psilocybin in areas like depression, end-of-life anxiety, addiction, and PTSD, which reflects research focus and session logistics, not a universal advantage.
People often describe psilocybin as inward and emotionally deep. LSD is commonly reported as clearer, more analytic, and energizing, which some prefer for insight, pattern recognition, and creativity.
Duration also matters. LSD sessions typically last 8 hours or longer, giving more time to explore a process, while psilocybin is often around 4 to 6 hours, which is easier to schedule and study.
Responses differ person to person, so fit and intention drive the choice. For a practical sense of what guided LSD work can look like, see this overview of LSD therapy. Hope that helps.