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Are psilocybin’s antidepressant effects strongest in the first 90 days?

Short answer: reports and several studies suggest benefits are often strongest in the first weeks up to roughly 90 days after a psilocybin or truffle session. Responses vary widely, and I cannot verify this for everyone. After that, the trajectory seems to depend on integration and ongoing habits. Deliberate follow-up such as reflection, supportive conversations, […]

Do 2C-B and psilocybin alter brain networks in similar but distinct ways?

Yes. In a 7 Tesla resting-state fMRI crossover study in healthy volunteers, both 2C-B and psilocybin reduced within-network coherence (notably in visual systems and parts of the default mode network) while increasing cross-network and subcortical to cortical connectivity. Both also increased the complexity of spontaneous brain signals. They were not identical, though. Psilocybin showed broader […]

Do you offer a private psychedelic couples therapy retreat in the Netherlands?

Yes. We offer private psychedelic couples sessions and retreats in the Netherlands. For most couples the recommended format is a private duo session, often with psilocybin from truffles that are legally available in the Netherlands. This can be hosted at one of our locations or at a suitable private accommodation you arrange. We usually begin […]

Why do LSD and psilocybin give me strong body effects but few visuals?

What you describe sounds like strong physiological activation with a muted “trip layer.” That can feel like big pupils, shaking and nausea, yet few visuals. It is not the same as no effect. Some people mainly get bodyload and emotional shifts while the visual component stays light. Common reasons include recent tolerance or microdosing carryover, […]

How many psychedelic sessions has Triptherapie guided?

Triptherapie states it has guided more than 3,500 psychedelic sessions as an organization as of May 2026. I cannot independently verify this figure. They also report that sessions are delivered by a team of multiple facilitators and can be arranged as individual, duo, or group formats. For an overview of current rates and what is […]

Can a single 25 mg psilocybin dose help chronic suicidal ideation?

Short answer: possibly, but evidence is preliminary. In a small open-label trial of adults with depression and chronic suicidal ideation, a single supervised 25 mg dose of synthetic psilocybin combined with intensive psychotherapy was associated with rapid reductions in suicidal thinking for many participants. An open-label report in The Journal of Clinical Psychiatry describes these […]

Does psilocybin act faster and last longer than placebo for depression?

Yes. In a small randomized study from Sweden, a single 25 mg psilocybin session with psychotherapy improved depression scores faster than an active placebo (100 mg niacin): the primary endpoint at day 8 favored psilocybin, and the advantage persisted to day 42 on clinician ratings, with self-reported improvement visible from day 2 to day 102, […]

Should I choose a group truffle ceremony or a private truffle session in Delft?

Choose a group truffle ceremony if you value connection, shared energy, and peer support. It can feel inspiring to journey with others and reflect together afterward. Go private if you want focused guidance, fewer distractions, and maximum privacy. If you are in Delft, some facilitators can offer a home session, but please confirm availability first […]

What types of psychedelic retreats are available at Triptherapie?

Triptherapie offers several formats: private one-on-one sessions, duo sessions for two trusted people, custom closed-group ceremonies you assemble, and open-group ceremonies where you join others. You can choose the setting at a Triptherapie location or at your own place, such as home, a hotel room, a holiday rental, or a private Airbnb, provided the space […]

Do you offer psilohuasca retreats, and what do they include?

Yes. Triptherapie offers psilohuasca retreats that use a combination of truffle-derived psilocybin and an MAO inhibitor to support deep introspection in a guided setting. Retreats typically include a small-group format with about one facilitator for every three participants, healthy meals, an overnight stay, and post-ceremony integration talks. Standard ceremonies use truffles, with the option to […]

Is a psychedelic session in Amersfoort possible?

Yes, a psychedelic session in Amersfoort is possible. We can host it at your home, an Airbnb, a hotel, or at one of our own locations in the Netherlands. Availability in Amersfoort depends on facilitator schedules. To check options or plan a date, please see the details here. Before booking, we do an intake to […]

How can Lion’s Mane support preparation and integration for a truffle ceremony?

Lion’s Mane is a non-psychedelic mushroom that some people use for focus and mental clarity around a truffle ceremony. Human evidence for specific benefits is limited and mixed, so any effect is not guaranteed. It is not a replacement for preparation, guidance, rest, nutrition, sleep, or integration, and it does not boost the truffle experience. […]