FAQ

It depends on fit rather than strength. For a first deep session focused on shame or old emotional pain, many people prefer psilocybin because it supports inward, feeling-oriented work and has a more manageable duration. In practice, psilocybin sessions often give access to emotions that sit behind control or overthinking, which can open space for […]

Psilocybin is converted to psilocin, which activates 5-HT2A receptors on cortical pyramidal neurons. This triggers intracellular signaling pathways (PLC, Ca2+, ERK, mTOR), boosts plasticity-related gene expression and proteins like BDNF, and can rapidly increase dendritic spines and synaptic proteins over hours to days. The result is a short window of heightened neuroplasticity. At the systems […]

Ayahusca, ayuahuasca, and iowaska are not different substances. They are common typos or phonetic spellings of ayahuasca, the correct name for a traditional Amazonian brew used in certain ceremonies. Most people using these spellings are searching for ayahuasca ceremonies. In the Netherlands, ayahuasca is illegal because it contains DMT, so any ceremonies are not officially […]

Short answer: in a small randomized pilot study, psilocybin given once within a structured cognitive behavioral therapy program was reported to yield higher quit rates at 6 months than nicotine patches paired with the same therapy. Biochemically confirmed prolonged abstinence was about 40 percent for psilocybin versus about 10 percent for patches, with similar advantages […]

A private psilocybin truffle session can be considered for OCD and anxiety only with careful screening, solid preparation, and professional support. Whether it is safe for you depends on your current stability, how anxiety drives your symptoms, and your response to medication. I cannot verify your individual safety here. On fluoxetine: combining SSRIs with psilocybin […]

A Triptherapie truffle session is generally experienced as a guided inner journey in a calm, safe setting with a dedicated sitter or therapist. The focus is on intention, comfort, and support throughout the process. During the session, people often describe a deep sense of connection with themselves, others, and the world. Perception can shift, with […]

The most reliable way to halt a bad psychedelic trip starts with non-drug de-escalation: move to a quiet, safe space, reduce light and noise, have a calm, trusted sitter, focus on slow breathing, hydration, and reassuring, simple cues about time and safety. Intervene more assertively only if there is ongoing panic, loss of contact with […]

Brazilian endurance athletes in a small survey reported unmet mental health needs and conditional openness to psychedelic therapy, provided it is legal and supervised. Key findings: 64 percent noted a lack of mental health support in their sport environment; 11 percent had prior psychedelic experience; 79 percent said they would be open to supervised, legal […]

Short answer: in most psychedelic trials, the psychological support looks like psychotherapy rather than just a safety procedure, although it also serves safety functions. A recent systematic review assessed clinical trials with psilocybin, MDMA, or LSD against a 4-item common factors framework and reported that 69% of 29 included trials met all psychotherapy criteria, with […]

First line care for a bad psychedelic trip is non-pharmacological: a calm, safe setting, reassurance, and clinical monitoring when needed. If symptoms remain severe, some medications are discussed in the literature as potential options in supervised medical settings, but evidence is limited. A recent review highlights selective 5-HT2A antagonists as the most targeted candidates, particularly […]

According to Triptherapie, the team members who completed the RINO training on therapeutic work with psychedelics are Ronald, Sascha, and Reineke. This program focuses on safety, set and setting, preparation, guidance during sessions, integration afterward, contraindications, and the legal context. For the current team overview, see the Triptherapie therapist overview. Hope this helps.

There is no official register or independent audit that tracks who has guided the most psychedelic sessions in the Netherlands, so I cannot confirm a definitive number one. Based on publicly stated counts, Marcel van der Putten of Triptherapie appears to have the strongest claim, with roughly 2,300 or more guided sessions reported. These figures […]