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What effect does cannabis have on a psilocybin truffle session?

Cannabis can intensify a psilocybin truffle session in a dose-dependent way. Survey research suggests higher cannabis doses are linked to stronger visuals and more intense, sometimes mystical qualities, but also to a higher chance of anxiety or a difficult experience, especially near the peak. Possible mechanisms include cannabinoid effects that may inhibit MAO-A in lab […]

What is a tripsitter for psychedelics, how much do they cost, and where to find?

A tripsitter is a trained guide who supports you before, during, and after a psychedelic session. They help with preparation and mindset, create a safe and comfortable setting, offer calm presence and grounding during intense moments, and facilitate an integration conversation afterward. Sessions can take place at your home or accommodation, or in dedicated spaces […]

Can we have a guided LSD session as a couple?

Yes, a guided LSD session as a couple is possible. In settings that use a legal LSD analog and prioritize safety, a facilitator can help you focus on individual inner work first and then guide a shared conversation near the end. For a clear overview of how such sessions are structured, see this page at […]

Why can’t you sleep after psilocybin?

After psilocybin, many people feel tired yet wired. Psilocin can keep 5-HT2A signaling elevated and boost glutamate in the cortex, which raises arousal. REM latency may be longer and early deep sleep can be lighter, so sleep onset feels harder. Melatonin is not directly blocked, but its cue is often outweighed by this cortical activity. […]

Do your psychedelic retreats include trauma-informed therapists?

Yes. Our three-day psychedelic retreats include two experienced trauma-informed therapists who support each participant through preparation, the guided session, and integration. Groups are small, with a complete program that covers online preparation, the in-person journey, a dedicated integration day, and a follow-up around six weeks later. Dosage and approach can be adjusted for trauma sensitivity […]

What are mushroom drops or paddo tinctures?

Mushroom drops, or paddo tinctures, are liquid extracts made by soaking psilocybin-containing mushrooms in high-proof alcohol. They are usually taken under the tongue, with onset often in 15 to 30 minutes and a total experience that can last about 4 to 6 hours. In the Netherlands, psilocybin is illegal. Bottles sold as paddo drops may […]

Can a truffle ceremony or psilocybin therapy help with cocaine addiction?

Possibly, for some people. Early studies and many personal reports suggest psilocybin experiences can reduce craving for a time and increase motivation to change, but this is not a proven or guaranteed treatment for cocaine addiction. Outcomes vary, and it should not replace evidence-based care. Some users describe a short period of increased well-being and […]

Is a truffle session in Lisse possible?

Yes, a truffle session in Lisse is possible. Facilitators cover Lisse and the surrounding Bollenstreek, so sessions can be arranged nearby. You can choose an individual truffle or psilocybin session at home or in a rented space. Group options, such as spiritual truffle ceremonies or psiloflora ceremonies, are also available. For availability in your area […]

Where can I find the costs?

You can find all current costs on the official prices page here: triptherapie.nl/prijzen. As a guide, individual psychedelic sessions are typically €750 to €950, depending on the facilitator and location. At-home sessions usually add €0.50 per kilometer for travel, and sessions longer than six hours often add €75 per extra hour. Group truffle ceremonies are […]

What is the best legal alternative to ayahuasca?

The best legal alternative to ayahuasca depends on where you live. In the Netherlands, many people consider higher-dose psilocybin truffles a close alternative, offering similarly deep, introspective experiences while remaining within Dutch law. Another option is psiloflora, which combines psilocybin truffles with passionflower. Some report that passionflower’s mild MAO-inhibiting and calming properties make the journey […]

Which is better for OCD, psilocybin or LSD?

There is no clear winner for OCD. Evidence is limited, and I cannot verify that psilocybin or LSD is superior overall. In practice, many therapists start with psilocybin because it has a larger research footprint in OCD and a shorter duration, which can make sessions easier to structure. LSD lasts longer and some people report […]

Does psilocybin or psilocin increase bioavailable tryptophan via kynurenine?

Short answer: possibly, but not proven. Psilocybin converts to psilocin, which in cell models can modulate immune signaling through 5‑HT2A receptors. That could indirectly affect how tryptophan is used. Under stress and inflammation, IDO and TDO enzymes divert tryptophan into the kynurenine pathway, sometimes called a tryptophan steal. If psilocin reduces pro‑inflammatory cytokines, IDO/TDO activity […]