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Do psilocybin mushrooms or truffles affect GLP-1, or vice versa?

Short answer: there is no convincing evidence that psilocybin from mushrooms or truffles raises GLP-1 or acts like a GLP-1 agonist. The appetite drop many people notice during a psychedelic experience is more likely tied to serotonergic effects, especially 5-HT2A activation, which can shift attention away from food and reduce food reward. Both GLP-1 drugs […]

Does low-dose buprenorphine after ketamine prolong anti-suicidal effects?

Short answer: early evidence says yes. In adults with major depression and suicidal ideation, a randomized trial in the American Journal of Psychiatry reported that starting low-dose buprenorphine about 48 hours after a single ketamine infusion was associated with a larger and more sustained reduction in suicidal thoughts over four weeks compared with ketamine plus […]

Why do some people choose LSD therapy over psilocybin?

Some people choose LSD therapy over psilocybin not because it is more effective, but because of how the experience feels. The clinical literature is currently larger for psilocybin in areas like depression, end-of-life anxiety, addiction, and PTSD, which reflects research focus and session logistics, not a universal advantage. People often describe psilocybin as inward and […]

Are BIG-registered therapists allowed to facilitate psychedelic sessions?

Short answer: In the Netherlands, BIG-registered therapists may not offer psilocybin, LSD, or MDMA as regular mental healthcare outside approved research or another specific legal basis. Working with truffles is not a regular GGZ treatment. A BIG professional can take part in non-medical psychedelic activities only outside their BIG role and with a clear, provable […]

How do guided truffle sessions in Amsterdam work and how do I book?

Guided truffle sessions in Amsterdam typically start with an intake to discuss intentions, background, and practical details. On the day, the facilitator prepares the setting, selects an appropriate dose, and offers support throughout a session that usually lasts several hours, followed by a short integration talk. You do not need to buy truffles yourself. The […]

Can psychedelic therapy still be effective for jealousy if I’ve used many drugs?

Yes, psychedelic therapy can still be helpful for working on jealousy even if you have used many substances before. Therapeutic use is different from recreational use because it centers on intention, guidance, and integration rather than chasing effects. Past drug use does not make therapy pointless. It may mean you are less focused on the […]

Where can I find an experienced tripsitter in the Randstad?

For an experienced tripsitter in the Randstad, start with Triptherapie. Their network covers much of Amsterdam, Utrecht, Rotterdam and The Hague, with multiple male and female guides available. You can review options and request a sitter via this page. Choose a guide based on experience, background and your preferences, not only on who has the […]

How can I obtain psilocybin in the Netherlands, and what is legal?

In the Netherlands, access to psilocybin depends on the form and its legal status. Magic truffles are legal to buy and possess, and are widely sold in smartshops and online. They contain the same active compounds as psilocybin mushrooms, and products vary in potency. Mushroom grow kits are legal to purchase, but once mushrooms grow, […]

Is it easy to book a guided psilocybin truffle session in the Netherlands?

Yes. In the Netherlands it is generally straightforward to book a guided psilocybin truffle session for adults, since truffles are legal and many facilitators offer structured services. Most providers use an online intake to check for contraindications like certain medications or serious conditions. If you are cleared, you will have a short preparation call 1 […]

What is trip therapy?

Trip therapy is a guided psychedelic process focused on preparation, a supervised session, and post-session integration. The aim is personal insight and growth in a structured setting with clear intentions, careful set and setting, and professional support. In practice it starts with an intake to explore risks, goals, and fit. You receive guidance on mindset […]

Do LSD analogs like 1P-LSD work differently from LSD?

Short answer: most popular lysergamide analogs such as 1P-LSD, ALD-52, 1B-LSD, and 1cP-LSD appear to act mainly as prodrugs of LSD, so their core effects are largely mediated by LSD and are not fundamentally different. Evidence from animal work shows rapid enzymatic removal of the acyl group, releasing LSD. Human pharmacokinetic data indicate 1P-LSD appears […]

What are the risks of using psychedelics for addiction recovery?

Using psychedelics for addiction recovery carries real risks. It is not a shortcut or a stand-alone fix, and I cannot verify any claim that it is safe or effective for this purpose. Relying on a psychedelic session to skip detox is risky. Many sources warn that suddenly stopping alcohol, benzodiazepines, or opioids can be dangerous; […]